2012年10月31日 星期三

Common food preservative may offer hope

Nisin, a common food preservative, may slow or stop the growth of squamous cell head and neck cancers, according to world-first research by a University of Michigan study team. The results were published this month in the journal Cancer Medicine with an accompanying press release by the University of Michigan on Oct. 30.

What makes this particularly good news is that the Food and Drug Administration and the World Health Organization approved nisin as generally regarded as safe for human consumption (GRAS) decades ago, says Dr. Yvonne Kapila, D.D.S., the study's principal investigator and a professor at the University of Michigan School of Dentistry. In fact nisin has been approved for use in human foods since 1969, having been given the food additive identification number 234 and is regarded as being particularly non-toxic.We mainly supply professional craftspeople with wholesale agate beads from china,China plastic moulds manufacturers directory.

This means that obtaining FDA approval to test nisin's suggested cancer-fighting properties on patients in a clinical setting won't take as long as a new therapy that hasn't been tried yet on people, she says.

Nisin is a natural antimicrobial agent, formed by fermentation using the bacterium Lactococcus lactis. It is one of the few commercial food preservatives which are not chemically synthesized. Nisin is obtained by culturing milk or dextrose with L. lactis, similar to the the yoghurt-making process.

Nisin has a fairly broad-spectrum effect on gram-positive bacteria, successfully inhibiting listeria monocytogenes, staphylococcus aureus, clostridium botulinun and lactic acid bacteria which are commonly associated with food spoilage. It has essentially no effect on gram-negative bacteria, moulds or yeasts, by itself.

Antibacterial agents like nisin alter cell properties in bacteria to render it harmless. However, it's only recently that scientists began looking to antibacterial agents like nisin to see if they altered properties in other types of cells,The MaxSonar ultrasonic sensor offers very short to long-range detection and ranging. such as cancer cells or cells in tumors.We mainly supply professional craftspeople with crys talbeads wholesale shamballa Bracele , Nisin affects the rate at which tumors are able to grow, inducing cell death in the tumor, selectively, without harming other cells, and limiting their ability to grow. Nisin may also create pores in the cancer cells which allow calcium to flood in. Calcium is a key regulator in cell death or survival, although it is not known precisely what role it plays.

Oral cancer is a leading cause of death worldwide,Our technology gives rtls systems developers the ability. and oral squamous cell carcinoma accounts for more than 90 percent of oral cancers. However, oral cancers are notoriouslly difficult to treat effectively and survival rates for oral cancer haven't improved in decades, according to the study.

The company is on schedule for its 200th green aircraft completion in December, a volume enabled by continuous improvement initiatives that have increased the efficiency of its completions process. The last 16 of Jet Aviation St. Louis’s completions have been delivered ahead of schedule, the company noted. Krugh added that the company’s completion experience “has made us experts at building aircraft and at building the tools we use to manage the aircraft production process. From improved data management to shop-floor layout, we have looked at every variable involved in the process and worked to make it better.”

Here at the show, Jet Aviation is debuting an interior configuration and paint scheme app for the iPad and iPhone that allows clients to visualize their options for cabin interior appointments and exterior finishes. Jet Aviation St. Louis is also touting its free tool calibration offer: any client who brings an aircraft in for maintenance before December 31 this year can receive free calibration of hand tools, such as torque wrenches and micrometers. “We’re offering to calibrate clients’ hand tools as a reminder about the importance of [the procedure],” said Krugh. “With certified metrologists on staff, calibration is just one of the many valuable services we have to offer.”

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